Composition of whey growth factor extract for reducing muscle inflammation

摘要

The invention relates to the production of compositions containing milk products for use as a nutritional supplement. More specifically, it relates to compositions containing whey growth factor extract, as well as their use in methods for reducing muscle inflammation in individuals undertaking resistance exercise training. According to one aspect of the invention, there is provided the use of a composition comprising whey growth factor extract, isolated from a milk product by cation exchange chromatography, to reduce exercise-induced muscle inflammation.

主权项

1. A method of reducing resistance training induced muscle inflammation in a subject, undergoing resistance training, in need thereof comprising:
administering to the subject an effective amount of a composition comprising at least 5 mg/kg body weight of whey growth factor extract (WGFE), wherein the WGFE is isolated from a bovine milk product selected from the group consisting of cheese whey, rennet casein whey, acid whey and skim milk, and wherein the WGFE is obtained by: a) applying the bovine milk product to cation exchange resin beads containing sulfopropyl functional groups; b) washing the cation exchange resin beads with a buffer of low ionic strength; and c) eluting and isolating the WGFE from the cation exchange resin beads with a buffer containing 0.4-0.5M NaCl at pH 6.5.