发明名称 Seamless capsule and manufacturing method therefor
摘要 The present invention is related to a seamless capsule which easily dissolves in the oral cavity etc. The present invention provides a seamless capsule comprising a capsule content solution, and a capsule shell enclosing the capsule content solution, wherein the capsule shell comprises a gelatin having a bloom value of 50 to 190 and wherein the seamless capsule has a capsule shell-dissolution time of 60 seconds or less when the dissolution time is determined by a disintegration test using water as a test solution.
申请公布号 US9510609(B2) 申请公布日期 2016.12.06
申请号 US201214347869 申请日期 2012.09.21
申请人 MORISHITA JINTAN CO., LTD. 发明人 Kamaguchi Ryosei;Nakano Osami;Hatanaka Hisaaki
分类号 A23L1/00;A61J1/00;A61K9/48;A61K9/50;B01J13/04;A61K9/00 主分类号 A23L1/00
代理机构 Hamre, Schumann, Mueller & Larson, P.C. 代理人 Hamre, Schumann, Mueller & Larson, P.C.
主权项 1. A process for producing a seamless capsule, comprising steps of; (i) using a coaxial nozzle comprising an inner nozzle and an outer nozzle having concentrically increasing diameters to simultaneously extrude both a capsule content solution from the inner nozzle and a preparation solution for the capsule shell from the outer nozzle to form a composite jet; and (ii) pouring the composite jet into a cooling solution, wherein the capsule content solution and the seamless capsule shell form a two layer structure, wherein the preparation solution for the capsule shell comprises gelatin having a bloom value of 50 to 190, water and ethanol, and wherein the mass ratio of water to ethanol is within the range of 40/60 to 95/5.
地址 Osaka JP