发明名称 |
Seamless capsule and manufacturing method therefor |
摘要 |
The present invention is related to a seamless capsule which easily dissolves in the oral cavity etc. The present invention provides a seamless capsule comprising a capsule content solution, and a capsule shell enclosing the capsule content solution, wherein the capsule shell comprises a gelatin having a bloom value of 50 to 190 and wherein the seamless capsule has a capsule shell-dissolution time of 60 seconds or less when the dissolution time is determined by a disintegration test using water as a test solution. |
申请公布号 |
US9510609(B2) |
申请公布日期 |
2016.12.06 |
申请号 |
US201214347869 |
申请日期 |
2012.09.21 |
申请人 |
MORISHITA JINTAN CO., LTD. |
发明人 |
Kamaguchi Ryosei;Nakano Osami;Hatanaka Hisaaki |
分类号 |
A23L1/00;A61J1/00;A61K9/48;A61K9/50;B01J13/04;A61K9/00 |
主分类号 |
A23L1/00 |
代理机构 |
Hamre, Schumann, Mueller & Larson, P.C. |
代理人 |
Hamre, Schumann, Mueller & Larson, P.C. |
主权项 |
1. A process for producing a seamless capsule, comprising steps of;
(i) using a coaxial nozzle comprising an inner nozzle and an outer nozzle having concentrically increasing diameters to simultaneously extrude both a capsule content solution from the inner nozzle and a preparation solution for the capsule shell from the outer nozzle to form a composite jet; and (ii) pouring the composite jet into a cooling solution, wherein the capsule content solution and the seamless capsule shell form a two layer structure, wherein the preparation solution for the capsule shell comprises gelatin having a bloom value of 50 to 190, water and ethanol, and wherein the mass ratio of water to ethanol is within the range of 40/60 to 95/5. |
地址 |
Osaka JP |