发明名称 |
CpG RECEPTOR (CpG-R) AND METHODS RELATING THERETO |
摘要 |
The present invention is directed to nucleic acid molecules and polypeptides encoding a CpG receptor (CpG-R). The CpG-R contains a THD, interacts with the MyD88 adapter protein, and may bind to CpG oligonucleotides. The present invention is also directed to antibodies against CpG-R and to methods of modulating an immune response and to methods of identifying compounds which bind to and/or modulate CpG-R.
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申请公布号 |
WO0132877(A3) |
申请公布日期 |
2002.01.03 |
申请号 |
WO2000US41735 |
申请日期 |
2000.11.01 |
申请人 |
CHIRON CORPORATION;MACKICHAN, MARY, LEE |
发明人 |
MACKICHAN, MARY, LEE |
分类号 |
C12N15/09;A61K39/395;A61K45/00;A61P1/04;A61P9/00;A61P11/00;A61P11/06;A61P25/00;A61P29/00;A61P31/00;A61P31/04;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07K14/705;C07K16/28;C12N15/12;C12Q1/02;G01N33/15;G01N33/50;G01N33/53;G01N33/566;(IPC1-7):C12N15/12;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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