发明名称 |
Molecular mimetics of meningococcal B epitopes which elicit functionally active antibodies |
摘要 |
Molecular mimetics of a surface-exposed epitope on loop 4 of PorA of Neisseria meningitidis serogroup B (MenB) P1.2 serosubtype and antibodies produced against the same are disclosed. Compositions containing such molecular mimetics or the antibodies thereto can be used to prevent MenB disease, as well as for diagnosis of MenB infection.
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申请公布号 |
US7534444(B2) |
申请公布日期 |
2009.05.19 |
申请号 |
US20020121456 |
申请日期 |
2002.04.11 |
申请人 |
NOVATTIS VACCINES AND DIAGNOSTICS, INC.;CHILDRENS HOSP & RES CT OAK |
发明人 |
GRANOFF DAN M.;MOE GREGORY;RAPPUOLI RINO |
分类号 |
A61K39/095;G01N33/53;A61K38/00;A61K39/00;A61K39/02;A61K39/38;A61K39/395;A61K39/40;A61P31/04;A61P43/00;C07K1/22;C07K2/00;C07K14/00;C07K14/22;C07K16/12;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/13;C12N15/63;C12P21/00;C12P21/02;C12P21/08;C12R1/36;G01N33/569 |
主分类号 |
A61K39/095 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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