| 发明名称 |
COMPOUND USEFUL AS INHIBITOR OF ATR KINASE |
| 摘要 |
PROBLEM TO BE SOLVED: To provide an inhibitor of ATR protein kinase.SOLUTION: Provided is a pyrazine compound of formula (I). The compound is useful as an inhibitor of ATR protein kinase. A pharmaceutically acceptable composition comprising the compound, a method of treating various diseases, disorders and conditions using the compound, and a method for preparing the compound are also provided.SELECTED DRAWING: None |
| 申请公布号 |
JP2016216495(A) |
申请公布日期 |
2016.12.22 |
| 申请号 |
JP20160141092 |
申请日期 |
2016.07.19 |
| 申请人 |
VERTEX PHARMACEUTICALS INC |
发明人 |
CHARRIER JEAN-DAMIEN;STEVEN DURRANT;KAY DAVID;O'DONNELL MICHAEL;KNEGTEL RONALD;SOMHAIRLE MACCORMICK;JOANNE PINDER;ANISA NIZARALI VIRANI;YOUNG STEVEN;HALEY MARIE BINCH;THOMAS CLEVELAND;LEV T D FANNING;DENNIS J HURLEY;PRAMOD JOSHI;URVI SHETH;ALINA SILINA;PHILIP MICHAEL REAPER |
| 分类号 |
C07D241/26;C07D401/12;C07D401/14;C07D403/04;C07D403/14;C07D405/04;C07D405/14;C07D409/04;C07D409/14;C07D413/04;C07D413/14;C07D417/14;C07D471/04;C07D487/04;C07D487/08;C07D487/10;C07D491/113;C07D513/04 |
主分类号 |
C07D241/26 |
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