发明名称 |
ANTIMICROBIAL PEPTIDES AND METHODS OF USE THEREOF |
摘要 |
A class of cationic, polyphemusin-like peptides having antimicrobial activit y is provided. Examples of such peptides include FRWCFRVCYKGRCRYKCR (SEQ ID NO:3), RRWCFRVCYKGFCRYKCR (SEQ ID NO:4), and RRWCFRVCYRGRFCYRKCR (SEQ ID NO:11). Also provided are methods for inhibiting the growth of microbes such as bacteria, yeast and viruses utilizing the peptides of the invention. The peptides are particularly useful for inhibiting endotoxemia in a subject.</S DOAB>
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申请公布号 |
CA2412531(A1) |
申请公布日期 |
2002.01.03 |
申请号 |
CA20012412531 |
申请日期 |
2001.06.27 |
申请人 |
THE UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
HANCOCK, ROBERT E. W.;ZHANG, LIJUAN |
分类号 |
C12N15/09;A61K38/00;A61K45/00;A61P31/04;C07K7/08;C12N1/20;C12N7/06;(IPC1-7):C07K7/08;A61P31/00;A61K38/10;C12N15/12 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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