摘要 |
Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise one or more of a WT1 polynucleotide, a WT1 polypeptide, an antigen-presenting cell presenting a WT1 polypeptide, an antibody that specifically binds to a WT1 polypeptide; or a T cell that specifically reacts with a WT1 polypeptide. Such compositions may be used, for example, for the prevention and treatment of metastatic diseases.
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申请人 |
CORIXA CORPORATION;GAIGER, ALEXANDER;MCNEILL, PATRICIA, D.;SMITHGALL, MOLLY;MOULTON, GUS;VEDVICK, THOMAS, S.;SLEATH, PAUL, R.;MOSSMAN, SALLY;EVANS, LAWRENCE;SPIES, A., GREGORY;BOYDSTON, JEREMY |
发明人 |
GAIGER, ALEXANDER;MCNEILL, PATRICIA, D.;SMITHGALL, MOLLY;MOULTON, GUS;VEDVICK, THOMAS, S.;SLEATH, PAUL, R.;MOSSMAN, SALLY;EVANS, LAWRENCE;SPIES, A., GREGORY;BOYDSTON, JEREMY |