摘要 |
The present invention relates to methods of determining if a patient has cancer or is at increased risk of developing cancer, particularly pancreatic cancer, the method comprising testing a FANC gene for the presence of a cancer-associated coding change, wherein said presence of one or more cancer-associated coding changes is indicative of cancer or an increased risk of cancer in said patient. The invention further relates to methods of treating a patient having cancer, particularly pancreatic cancer, who has one or more cancer-associated coding changes in the FANC genes comprising the step of administering a therapeutically effective amount of a chemotherapeutic cross-linking agent. |
申请人 |
THE JOHNS HOPKINS UNIVERSITY;KERN, SCOTT, E.;VAN DER HEIJDEN, MICHIEL, S. |
发明人 |
KERN, SCOTT, E.;VAN DER HEIJDEN, MICHIEL, S. |