Determination of metal and metalloid concentrations using ICPMS

摘要

A system for determining an analyte by inductively coupled plasma mass spectrometry (ICPMS) includes a sample introduction device having a heated cyclonic spray chamber. The system is configured to introduce sample that includes a metal and/or a metalloid having an organic interferent. The system also includes an inductively coupled plasma mass spectrometry device with a collision/reaction cell configured to receive a mixture of gases including both ammonia and hydrogen. A method includes introducing a sample to plasma to produce a characteristic spectrum associated with an elemental composition of the sample. The method also includes introducing both ammonia and hydrogen to a collision/reaction cell to remove carbon-based interferences to detection of the sample prior to determining the elemental composition of the sample.

主权项

1. A method for determining an analyte by inductively coupled plasma mass spectrometry (ICPMS), the method comprising:
introducing a sample to a plasma to produce a characteristic spectrum associated with an elemental composition of the sample, the sample including at least one of a metal or a metalloid having an organic interferent; and prior to determining the elemental composition of the sample, introducing both ammonia and hydrogen to a collision/reaction cell to remove at least one carbon-based interference to detection of the analyte.