METHOD FOR THE TREATMENT OF DIABETES MELLITUS

摘要

This disclosure is in the field of medical therapy; in particular, it concerns the use of encapsulated cells in cell therapy. More in particular, this disclosure relates to the second medical use of a composition comprising encapsulated cells. Even more in particular, the disclosure relates to the use of a foreign body, suitable for implantation into a subject at a predefined location, wherein the foreign body comprises cells encapsulated in high-M alginate for inducing or stimulating angiogenesis.

主权项

1. A method of treating a subject with diabetes mellitus, the method comprising:
implanting a composition into the body of the subject at a predefined location, wherein the composition comprises: aggregates of fetal, newborn, or perinatal pancreatic cells encapsulated in alginate particles with a mannuronic acid content of at least 50%, and a viscosity of 100 mPa·s or less, and wherein the aggregates are smaller than 100 micrometers.