Methods and compositions for treating wounds utilizing chitosan compounds

摘要

Described herein are methods of treating wounds, the method comprising administering to a subject an effective amount of a composition comprising a soluble or derivatized chitosan wherein the soluble or derivatized chitosan when administered contacts the wound, thereby treating the wound.

主权项

1. A method of treating mucositis or ulceration in the gastrointestinal (GI) tract, the method comprising administering to a subject an effective amount of a composition comprising a soluble or derivatized chitosan, wherein the derivatized chitosan comprises a chitosan of the following formula (I): wherein: n is an integer between 20 and 6000; and each R1 is independently selected for each occurrence from hydrogen, acetyl, and a group of formula (II): wherein at least 25% of R1 substituents are H, at least 1% of R1 substituents are acetyl, and 4-30% of R1 substituents are a group of formula (II), thereby treating mucositis or ulceration.