发明名称 |
Nukleotidsekvenser fra coryneforme bakterier som koder for proteiner der deltager i L-serinstofskiftet |
摘要 |
Nucleic acid (I), optionally recombinant and replicable in Corynebacterium, has the sequence for L-serine dehydratase (II): (a) partly or completely deleted or mutated; or (b) expressed at a lower level, relative to the natural sequence, or not at all. Independent claims are also included for: (1) gene structure (GS) comprising (I) and linked regulatory elements; (2) vector containing (I) or GS, also sequences for selection, replication in a host cell or integration into the host cell genome; (3) (II) with reduced activity, encoded by (I); (4) microorganism that contains (I); (5) probe for identification and/or isolation of genes that encode proteins involved in biosynthesis of L-serine, derived from (I) and labeled to allow detection; and (6) microbial production of L-serine by growing microorganisms of (4). |
申请公布号 |
DK200900060(U3) |
申请公布日期 |
2009.07.10 |
申请号 |
DK20090000060U |
申请日期 |
2009.03.20 |
申请人 |
FORSCHUNGSZENTRUM JUELICH GMBH |
发明人 |
PETERS-WENDISCH, PETRA;EGGELING, LOTHAK;SAHM, HERMANN;NETZER, ROMAN |
分类号 |
C07H21/04;C12N1/21;C12N9/88;C12N15/09;C12N15/53;C12N15/60;C12N15/74;C12P13/06 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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