Tissue sealant containing an alkali metal salt of carboxymethylcellulose, fibrinogen and thrombin

摘要

A tissue sealant comprising thrombin, fibrinogen, and carboxylmethyl cellulose or alkali metal or alkali earth metal salt thereof is disclosed. The tissue sealant of the present invention promotes a hemostasis of an injury to a skin surface or a viscus, a healing of an injury, an endothelium formation of a blood vessel, an adhesive activity of animal cells, such as endothelial cells or fibroblasts in vitro, and an adhesion and agglutination of platelets.