AGENTS AND METHODS BASED ON THE USE OF THE EDA DOMAIN OF FIBRONECTIN

摘要

The invention relates to the use of a polypeptide in the production of an immunostimulatory agent, said polypeptide comprising a sequence corresponding to the EDA domain of fibronectin, a fragment of the EDA domain which can bind to TLR4 or a variant of said EDA domain or a fragment which can bind to TLR4 and which has a homology of more than 70 % with any form or natural fragment of the EDA domain. The invention also relates to the production methods and applications of said agent.