| 发明名称 |
Method for the Preparation of 1-Benzotriazolyl Carbonate Esters of Poly(ethylene glycol) |
| 摘要 |
The present invention provides a biologically active conjugate, obtainable by reacting an amino acid derivative of the following structure
wherein PEG is poly(ethylene glycol) and Z is selected from the group consisting ofH, N-succinimidyl, or 1-benzotriazolyl,
with a protein. |
| 申请公布号 |
EP2070968(A2) |
申请公布日期 |
2009.06.17 |
| 申请号 |
EP20090154211 |
申请日期 |
2000.12.18 |
| 申请人 |
NEKTAR THERAPEUTICS AL, CORPORATION |
发明人 |
KOZLOWSKI, ANTONI |
| 分类号 |
C08G65/333;C12N9/96;A61K47/48;C08F8/30;C08G65/325;C08G65/329;C08G65/332 |
主分类号 |
C08G65/333 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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