PHARMACEUTICAL COMPOSITIONS CONTAINING 3-(2, 2-DIFLUOROBENZO[d][1, 3]DIOXOL-5-YL)CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDINE-2-YL)BENZOIC ACID, AND ADMINISTRATION THEREOF

摘要

FIELD: pharmaceutics.SUBSTANCE: pharmaceutical composition containing the compound 1,3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridine-2-yl)benzoic acid, and at least one excipient selected from filler, diluent, disintegrating agent, surfactant, binder, imparting slipperiness substance and lubricant, wherein composition is suitable for oral administration to patient in need thereof for treating CFTR-mediated diseases, such as cystic fibrosis. Methods of patient in need treating thereof include administering.EFFECT: including compound 1 having oral pharmaceutical finished dosage form.84 cl, 27 dwg, 18 tbl