Tissue diagnostics using evanescent spectroscopy

摘要

A method for in-vivo analysis of a biomedical sample characterized by contacting the sample with a chalcogenide glass fiber directly or through a crystal or other medium, with the chalcogenide fiber having input and output ends and light transmitted thereby with some of the light leaving the fiber to form evanescent field, which fiber transmits a signal in response to absorption of some of the light in the evanescent field by the sample, and processing the signal with a Fourier Transform IR Spectrometer to obtain a spectrum which indicates surface character of the sample without water masking the signal.