发明名称 FLUORESCENT OLEAMIDE DERIVATIVE AND USE THEREOF
摘要 An oleamide can emit fluorescence without largely deteriorating its biological activity by introducing a fluorescent group into the oleamide via a carbon chain, as shown in the formula (I). The fluorescent group (R) may be a dansyl group of the formula (II) or an NBD group of the formula (III). The compound is useful for any application such as a method for fluorescence observation of a cell, a gap binding inhibitor, a tool for the study of the intracellular action mechanism of an oleamide derivative, a pharmaceutical product, a food, a beverage and a supplement.
申请公布号 WO2008016139(A1) 申请公布日期 2008.02.07
申请号 WO2007JP65264 申请日期 2007.08.03
申请人 OSAKA UNIVERSITY;NARD INSTITUTE, LTD.;KITA, YASUYUKI;NOJIMA, HIROSHI;OHBA, YUSUKE;OKAMOTO, TAKASHI 发明人 KITA, YASUYUKI;NOJIMA, HIROSHI;OHBA, YUSUKE;OKAMOTO, TAKASHI
分类号 C07C311/39;A23L1/30;A61K31/4245;A61K49/00;A61P35/00;A61P35/04;A61P43/00;C07D271/12;C07D303/46;C07D413/12 主分类号 C07C311/39
代理机构 代理人
主权项
地址