发明名称 |
FLUORESCENT OLEAMIDE DERIVATIVE AND USE THEREOF |
摘要 |
An oleamide can emit fluorescence without largely deteriorating its biological activity by introducing a fluorescent group into the oleamide via a carbon chain, as shown in the formula (I). The fluorescent group (R) may be a dansyl group of the formula (II) or an NBD group of the formula (III). The compound is useful for any application such as a method for fluorescence observation of a cell, a gap binding inhibitor, a tool for the study of the intracellular action mechanism of an oleamide derivative, a pharmaceutical product, a food, a beverage and a supplement. |
申请公布号 |
WO2008016139(A1) |
申请公布日期 |
2008.02.07 |
申请号 |
WO2007JP65264 |
申请日期 |
2007.08.03 |
申请人 |
OSAKA UNIVERSITY;NARD INSTITUTE, LTD.;KITA, YASUYUKI;NOJIMA, HIROSHI;OHBA, YUSUKE;OKAMOTO, TAKASHI |
发明人 |
KITA, YASUYUKI;NOJIMA, HIROSHI;OHBA, YUSUKE;OKAMOTO, TAKASHI |
分类号 |
C07C311/39;A23L1/30;A61K31/4245;A61K49/00;A61P35/00;A61P35/04;A61P43/00;C07D271/12;C07D303/46;C07D413/12 |
主分类号 |
C07C311/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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