The present invention relates to the identification of polynucleotides and polypeptides having increased expression in tumor blood vessels. The invention further relates to the use of the identified polynucleotides and polypeptides, and inhibitors of the polynucleotides and polypeptides, in the regulation of angiogenesis and the diagnosis and treatment of angiogenesis-related diseases such as cancer.
申请公布号
WO2009139915(A3)
申请公布日期
2010.01.28
申请号
WO2009US03047
申请日期
2009.05.15
申请人
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL;DEMORE, NANCY, KLAUBER;PATTERSON, CAM;BHATI, RAJENDRA;BONE, BRADLEY, G.
发明人
DEMORE, NANCY, KLAUBER;PATTERSON, CAM;BHATI, RAJENDRA;BONE, BRADLEY, G.