发明名称 |
uso de materiais com comportamento ionóforo para zinco |
摘要 |
Disclosed is a method for delivering excess zinc to eukaryotic cells to inhibit the metabolism of the cell, the method comprising treating the cells with a zinc ionophoric that is capable of delivering a zinc ion across a cellular membrane wherein the minimum inhibitory concentration (MIC) of the zinc ionophoric material is less than about 500 ppm. Further disclosed is a method for delivering excess zinc to eukaryotic cells to inhibit the metabolism of the cell, the method comprising treating the cells with a zinc ionophoric material that is capable of delivering a zinc ion across a cellular membrane wherein the zinc ionophoric material is in combination with a zinc containing material and further wherein there is an increase in an intracellular zinc level by 1.5 fold more than would occur in the absence of the zinc ionophoric material. |
申请公布号 |
BRPI0309444(A2) |
申请公布日期 |
2016.07.12 |
申请号 |
BR20030309444 |
申请日期 |
2003.03.18 |
申请人 |
ARCH CHEMICALS, INC.;THE PROCTER & GAMBLE COMPANY |
发明人 |
CARL HINZ MARGRAF III;DAVID F. GAVIN;DAVID JOSEPH KAUFMAN;GEORGE POISON;JOHN D. NELSON;JAMES ROBERT SCHWARTZ;KATHERINE P. ROBERTS;PATRICIA A. TURLEY;RANDALL GLENN MARSH |
分类号 |
A61K8/06;A61K31/28;A61K8/00;A61K8/36;A61K8/44;A61K8/46;A61K8/49;A61K8/58;A61K8/60;A61K8/64;A61K31/145;A61K31/27;A61K31/315;A61K31/351;A61K31/357;A61K31/423;A61K31/44;A61K31/47;A61K33/30;A61P17/00;A61P31/00;A61P31/02;A61P31/10;A61P43/00;A61Q5/00;A61Q5/02;A61Q17/00 |
主分类号 |
A61K8/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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