| 发明名称 |
Brachiatin D and Process for Production Thereof |
| 摘要 |
The present invention relates to a peptaibol having sequence AcAib-Asn-Aib-Leu-Aib-Pro-Aib-Asn-Leu-Pro-Ileuol, isolated from endophytic fungus Trichoderma longibrachiatum having accession number MTCC 5721. The peptaibol is named as brachiating D. The present also related to a process for isolating the peptaibol from and use of the peptaibol as a pharmacologically active compound as a strong immunosuppressants and as an anticancer agents. |
| 申请公布号 |
US2016215017(A1) |
申请公布日期 |
2016.07.28 |
| 申请号 |
US201414914094 |
申请日期 |
2014.08.29 |
| 申请人 |
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH |
发明人 |
SINGH Deepika;SHARMA Jai Prakash;JAGLAN Sundeep;DAR Abid Hamid;KHAJURIA Anamika;SINGH Varun Pratap;VISHWAKARMA Ram Asrey |
| 分类号 |
C07K7/06;C12R1/885 |
主分类号 |
C07K7/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated peptaibol having sequence AcAib-Asn-Aib-Leu-Aib-Pro-Aib-Asn-Leu-Pro-Ileuol,
wherein AcAib is acetylated α aminoisobutyric acid, Aib is α aminoisobutyric acid, Asn is Asparagine, Leu is Leucine, Pro is Proline and Ileuol is Isoleucinol, represented by structure I. |
| 地址 |
New Delhi IN |
