Compositions and methods for combined inhibition of mutant EGFR gene and IL-6 expression
摘要
The invention relates to combinations of a double-stranded ribonucleic acid (dsRNA) targeting a mutant Epidermal Growth Factor Receptor (EGFR), and a double-stranded ribonucleic acid (dsRNA) targeting interleukin-6 (IL-6), and their use in treating cancer.
申请公布号
EP2690175(B1)
申请公布日期
2016.12.28
申请号
EP20130179293
申请日期
2009.09.02
申请人
Alnylam Pharmaceuticals, Inc.;Alnylam Europe AG.;The Regents of the University of California
发明人
Sah, Dinah;Tan, Pamela;Perez, Maria Del Mar Inda;Furnari, Frank;Cavenee, Webster;Bonavia, Rudy
