发明名称 |
Stabilized naloxone formulations |
摘要 |
Physically and chemically stable pharmaceutical compositions useful for administering naloxone by injection are described. These compositions are essentially aqueous solutions having a pH between 3.0-3.5, and containing naloxone, an acidic or buffer component, a tonicity-adjusting agent, and a stabilizing agent, said composition being optionally sterilized by autoclaving.
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申请公布号 |
US5866154(A) |
申请公布日期 |
1999.02.02 |
申请号 |
US19960673601 |
申请日期 |
1996.06.25 |
申请人 |
THE DUPONT MERCK PHARMACEUTICAL COMPANY |
发明人 |
BAHAL, SURENDRA MOHAN;WU, LEI-SHU |
分类号 |
A61K9/00;A61K31/485;A61K47/00;A61K47/02;A61K47/12;A61K47/18;A61K47/26;(IPC1-7):A61F2/02;A61K31/70 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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