FOUR BRANCHED DENDRIMER-PEG FOR CONJUGATION TO PROTEINS AND PEPTIDES

摘要

The invention relates to a dendrimer-like polymer structure having four monomethoxypolyethylenglycol branches, which can be represented as (I). The carboxylic group of the aforementioned structure can be functionalised in order to obtain conjugates of pharmaceutical interest. The binding of said dendrimer-like polyethylenglycol to therapeutic proteins improves the in vitro andin vivo stability of the latter.