发明名称 |
Novel Vaccine Containing Adjuvant Capable Of Inducing Mucosal Immunity |
摘要 |
The present invention provides an adjuvant that possesses a greater adjuvant potential than that of a conventional adjuvant, and that is capable of producing a protective reaction across different strains. This problem has been solved by the finding that a double-stranded RNA (for example, Poly(I:C)) unexpectedly exhibits the above capability when used in combination with a subunit antigen. Accordingly, the present invention provides a vaccine for mucosal administration containing A) a double-stranded RNA and B) a subunit antigen or inactivated antigen of a pathogen. |
申请公布号 |
US2007219149(A1) |
申请公布日期 |
2007.09.20 |
申请号 |
US20040567766 |
申请日期 |
2004.08.10 |
申请人 |
TORAY INDUSTRIES, INC. |
发明人 |
HASEGAWA HIDEKI;KURATA TAKESHI;SATA TETSUTAROU;MORIYAMA MASAMI;TAMURA SHIN-ICHI;TANIMOTO TAKESHI |
分类号 |
A61K48/00;A61K39/02;A61K39/12;A61K39/13;A61K39/145;A61K39/165;A61K39/21;A61K39/215;A61K39/295;A61K39/39;A61P31/12 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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