发明名称 Method of evaluating prostatic disease
摘要 According to the method of evaluating prostatic disease of the present invention, amino acid concentration data on concentration values of amino acids in blood collected from a subject to be evaluated is measured, and the state of prostatic disease including at least one of prostatic cancer and prostatic hypertrophy in the subject is evaluated based on the concentration value of at least one of Tau, Thr, Ser, Asn, Glu, Pro, Gly, Ala, Cit, ABA, Val, Met, Ile, Leu, Phe, His, Trp, Orn, Lys, and Cys2 contained in the measured amino acid concentration data of the subject.
申请公布号 US9465031(B2) 申请公布日期 2016.10.11
申请号 US201012971419 申请日期 2010.12.17
申请人 Ajinomoto Co., Inc. 发明人 Okamoto Naoyuki;Miura Takeshi;Miyagi Yohei;Imaizumi Akira;Yamamoto Hiroshi;Tanaka Takayuki;Muramatsu Takahiko;Ando Toshihiko;Takahashi Noriko
分类号 G01N33/48;G01N33/574;G01N33/68 主分类号 G01N33/48
代理机构 Foley & Lardner LLP 代理人 Foley & Lardner LLP
主权项 1. A method of evaluating prostatic disease, comprising: obtaining concentration values of amino acids in blood of a subject to be evaluated; evaluating, by a central processing unit (CPU) executing a prostatic disease-evaluating program stored on a computer-readable recording medium, a state of prostatic disease including at least one of prostatic cancer and prostatic hypertrophy in the subject, using at least concentration values of at least Trp and Ala contained in amino acid concentration data on the concentration values of the amino acids in blood of the subject, wherein the concentration value criterion evaluating step further includes: a discriminant value calculating step of calculating, by the CPU, a discriminant value that is a value of a multivariate discriminant, using at least both (i) the concentration values of at least Trp and Ala contained in the amino acid concentration data of the subject and (ii) the multivariate discriminant for evaluating the state of prostatic disease containing at least Trp and Ala as explanatory variables.
地址 Tokyo JP