Factor vii-binding reagent

摘要

The invention relates to novel compounds that potentiate zinc ion inhibition of the activity of factor VIIa or tissue factor-factor VIIa complex having the formula Ia and Ib and pharmaceutical salts thereof as well as pharmaceutical compositions comprising said novel compounds. The invention is further related to the use of said compositions for inhibiting clotting activity, tissue factor activity and factor VIIa activity.