| 摘要 |
PROBLEM TO BE SOLVED: To obtain an optically active glycidic ester used for a raw material, etc., for medicines, agrochemicals, etc., in high yield by treating a racemic glycidic ester in the presence of microorganisms such as the one belonging to genus corynebacterium having stereoselective hydrolytic open ring ability of the compound. SOLUTION: This optically active glycidic ester of formula II (a carbon atom with (*) represents the asymmetric carbon atom) and/or optically active glyceric ester of formula III is obtained by performing stereoselective hydrolytic ring opening of racemic glycidic ester of formula I (R is an alkyl, a cycloalkyl or an aryl) in the presence of a cultured material, microbial cell or a treated material of the microbial cell, of microorganisms such as the one belonging to genus corynebacterium, agrobacterium or aurebacterium and having stereoselective hydrolytic open ring ability of the compound in high yield and optical purity. |
