| 发明名称 |
ANTITUMORAL ANALOGS OF ET-743 |
| 摘要 |
<p>Antitumour compounds have the five membered fused ring ecteinascidin structu re of the formula (XIV). The present compounds lack a 1,4-bridging group as fou nd in the ecteinascidins. They have at the C-1 position a substituent selected from an optionally protected or derivatised aminomethylene group or an optionally protected or derivatised hydroxymethylene group.</p> |
| 申请公布号 |
CA2405002(A1) |
申请公布日期 |
2001.11.22 |
| 申请号 |
CA20012405002 |
申请日期 |
2001.05.15 |
| 申请人 |
PHARMA MAR, S.A. |
发明人 |
PEREZ, MARTA;CUEVAS, CARMEN;MANZANARES, IGNACIO;RODRIGUEZ, ALBERTO;MARTIN, MARIA JESUS;MUNT, SIMON |
| 分类号 |
C07D451/14;A61K;A61K31/4748;A61K35/00;A61P35/00;C07D;C07D241/00;C07D291/00;C07D317/00;C07D471/18;C07D491/18;C07D491/22;C07D493/22;C07D515/22;(IPC1-7):C07D515/22;C07D221/00 |
主分类号 |
C07D451/14 |
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