| 发明名称 |
THIENODIBENZOAZULENE COMPOUNDS AS TUMOR NECROSIS FACTOR INHIBITORS |
| 摘要 |
<p>The present invention relates to the dibenzoazulene compounds represented by formula I as well as to their pharmaceutical preparations for the inhibition of tumor necrosis factor alpha (TNF-alpha) and interleukine 1 (IL-1) in mammals at all diseases and conditions where these mediators are excessively secreted. The compounds of the present invention also demonstrate an analgetic action and can be used to relieve pain.</p> |
| 申请公布号 |
SI1284977(T1) |
申请公布日期 |
2009.10.31 |
| 申请号 |
SI20010030930T |
申请日期 |
2001.05.16 |
| 申请人 |
GLAXOSMITHKLINE ISTRAZIVACKI CENTER ZAGREB D.O.O. |
发明人 |
MERCEP MLADEN;MESIC MILAN;PESIC DIJANA;ZUPANOVIC ZELJKO;HRVACIC BOSKA |
| 分类号 |
A61K31/381;A61K31/55;A61P1/04;A61P11/06;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P27/02;A61P29/00;A61P35/00;A61P37/02;A61P43/00;C07B61/00;C07D495/04 |
主分类号 |
A61K31/381 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
