发明名称 |
Pyridazin-3(2H)-One Derivatives And Their Use As Pde4 Inhibitors |
摘要 |
The invention relates to new therapeutically useful pyridazin-3(2H)-one derivatives, to processes for their preparation and to pharmaceutical compositions containing them. These compounds are potent and selective inhibitors of phosphodiesterase 4 (PDE4) and are thus useful in the treatment, prevention and suppression of related pathological conditions, diseases and disorders, in particular asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, topic dermatitis, psoriasis or irritable bowel disease.
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申请公布号 |
US2009029996(A1) |
申请公布日期 |
2009.01.29 |
申请号 |
US20050629527 |
申请日期 |
2005.06.21 |
申请人 |
AGUILAR IZQUIERDO NURIA;CARRASCAL RIERA MARTA;DAL PIAZ VITTORIO;GRACIA FERRER JORDI;LUMERAS AMADOR WENCESLAO;MASDEU MARGALEF MARIA DEL CARMEN;WARRELLOW GRAHAM |
发明人 |
AGUILAR IZQUIERDO NURIA;CARRASCAL RIERA MARTA;DAL PIAZ VITTORIO;GRACIA FERRER JORDI;LUMERAS AMADOR WENCESLAO;MASDEU MARGALEF MARIA DEL CARMEN;WARRELLOW GRAHAM |
分类号 |
A61K31/5377;A61K31/501;A61P1/00;A61P11/00;A61P17/00;A61P19/02;C07D237/24;C07D401/12;C07D401/14;C07D403/02;C07D405/14;C07D409/14;C07D413/14;C07D471/04;C07D495/04 |
主分类号 |
A61K31/5377 |
代理机构 |
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代理人 |
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地址 |
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