发明名称 |
ORAL COMPOSITIONS OF CLINDAMYCIN |
摘要 |
<p>A taste masked pharmaceutical composition of clindamycin, or a pharmaceutically acceptable salt(s), hydrate(s), solvate(s) and physiologically functional derivative(s) and precursors thereof, which includes all polymorphic forms, whether crystalline or amorphous comprising polyhydric alcohol(s); and one or more other pharmaceutically acceptable excipient(s). A process for preparation of a taste masked pharmaceutical composition of clindamycin or a pharmaceutically acceptable salt(s) thereof the said process comprising the steps of a) dry mixing clindamycin, polyhydric alcohol and other pharmaceutically acceptable excipient(s) to get a dry mixture; b) granulating the dry mixture above with a granulating liquid prepared by mixing the suitable pharmaceutically acceptable excipient(s) with aqueous /non-aqueous fluid to obtain a wet mass; c) drying the wet mass to obtain the discrete particles; d) lubricating the discrete particles obtained with a suitable lubricating agent and/or flavour(s).</p> |
申请公布号 |
WO2010010568(A1) |
申请公布日期 |
2010.01.28 |
申请号 |
WO2008IN00579 |
申请日期 |
2008.09.10 |
申请人 |
LUPIN LIMITED;WALZADE, KALPANA;KULKARNI, RAJESH;KULKARNI, SHIRISHKUMAR |
发明人 |
WALZADE, KALPANA;KULKARNI, RAJESH;KULKARNI, SHIRISHKUMAR |
分类号 |
A61K9/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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