A PROCESS FOR PREPARING SUCCINIC ACID AND SUCCINATE ESTER

摘要

This invention relates to a process for preparing succinic acid and succinate ester from a succinic acid salt in fermentation broth. In the first stage of this invention, renewable carbon resources are utilized to produce succinic acid through biological fermentation. The succinic acid salt in the fermentation process is subjected to double displacement reaction with a strong acid leading to release of succinic acid. Succinic acid is recovered by fractional crystallization integrated with simulated moving bed chromatography to produce succinic acid and succinate ester.

主权项

1. A process for preparing succinic acid comprising the steps of:
a. fermentation of carbohydrate substrates using a biocatalyst to produce a succinate salt; b. clarification of fermentation broth to remove biocatalyst, proteins, and insolubles; c. concentration of said clarified fermentation broth from step (b); d. acidification of concentrated fermentation broth from step (c); e. controlled crystallization of succinic acid in the acidified and concentrated fermentation broth from step (d); f. separating crystalline succinic acid from mother liquor; and g. subjecting said mother liquor to simulated moving bed chromatography to recover remaining succinic acid; and h. crystallizing said succinic acid recovered in step (g).