发明名称 |
ANTI-DIARRHEIC PRODUCT AND METHOD OF TREATING ROTAVIRUS-ASSOCIATED INFECTION |
摘要 |
An anti-diarrheic product comprises a foodstuff and an anti-rotaviral agent such as human defatted fat globule membranes, the human milk macromolecular fraction, skim milk, curd, whey, the milk mucin complex, the 46 Kd app.MW glycoprotein, a polypeptide having an amino acid sequence having the rotavirus binding specificity of the 46 Kd app.MW HMFG glycoprotein or mixtures thereof. An anti-diarrheal kit comprises the anti-rotaviral agent of this invention and instructions for its use, and optionally a foodstuff. A method for inhibiting or countering rotavirus infection in mammalian cells comprises contacting the cells with an anti-rotaviral amount of the agent of this invention. A therapeutic method for inhibiting the onset of or countering rotavirus infection comprises administering to a subject afflicted with or at risk for rotavirus infections such as those occurring, for example, in infants and children (infantile gasteroenteritis) and immunodeficient persons or those who have received a transplant, an anti-rotaviral effective amount of the agent of this invention. |
申请公布号 |
WO9409651(A1) |
申请公布日期 |
1994.05.11 |
申请号 |
WO1993US10732 |
申请日期 |
1993.10.29 |
申请人 |
CANCER RESEARCH FUND OF CONTRA COSTA;JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE;NEWBURG, DAVID, S.,;PETERSON, JERRY, A.;YOLKEN, ROBERT, H. |
发明人 |
NEWBURG, DAVID, S.,;PETERSON, JERRY, A.;YOLKEN, ROBERT, H. |
分类号 |
A23L1/305;A61K35/20;A61K35/55;A61K38/00;A61K38/17;C07K14/47 |
主分类号 |
A23L1/305 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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