发明名称 |
HMGN2 peptides and related molecules that selectively home to tumor blood vessels and tumor cells |
摘要 |
The present invention provides a conjugate which contains a therapeutic moiety linked to a homing molecule that selectively homes to tumor blood vessels and tumor cells and that specifically binds the receptor bound by peptide KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK (SEQ ID NO: 9). Methods of directing a conjugate of the invention to tumor blood vessels and tumor cells and of using a conjugate to treat cancer also are provided.
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申请公布号 |
US2004186056(A1) |
申请公布日期 |
2004.09.23 |
申请号 |
US20030400083 |
申请日期 |
2003.03.20 |
申请人 |
RUOSLAHTI ERKKI;PORKKA KIMMO;CHRISTIAN SVEN |
发明人 |
RUOSLAHTI ERKKI;PORKKA KIMMO;CHRISTIAN SVEN |
分类号 |
A61K47/48;C07K14/47;(IPC1-7):A61K38/10;C07K7/08 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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