摘要 |
PROBLEM TO BE SOLVED: To provide an inhibitor of phosphatidylinositol 3-kinase (PI3Kα), a dual specificity protein kinase.SOLUTION: This invention relates to a compound of formula I, wherein Ris H, optionally substituted alkyl, optionally substituted aryl, or the like; X is -NR-; Ris H, haloalkyl, optionally substituted alkyl, or the like; Ris H, optionally substituted alkyl, or the like; Ris H, halo, haloalkyl, haloalkoxy, or the like; Ris H, halo, haloalkyl, haloalkoxy, optionally substituted aryl, or the like; and Ris H, halo, haloalkyl, or haloalkoxy.SELECTED DRAWING: None |