| 发明名称 | Piperidine inhibitors of Janus kinase 3 | ||
| 摘要 | The present invention relates to new piperidine inhibitors of Janus kinase 3 activity, pharmaceutical compositions thereof, and methods of use thereof.; | ||
| 申请公布号 | US9493469(B2) | 申请公布日期 | 2016.11.15 |
| 申请号 | US201514596784 | 申请日期 | 2015.01.14 |
| 申请人 | Auspex Pharmaceuticals, Inc. | 发明人 | Rao Tadimeti;Zhang Chengzhi |
| 分类号 | C07D487/00;C07D487/04 | 主分类号 | C07D487/00 |
| 代理机构 | Baker & Hostetler LLP | 代理人 | Baker & Hostetler LLP |
| 主权项 | 1. A compound of Formula II: or a salt thereof, wherein: Z1 is an amino protecting group;R3-R16 are independently selected from the group consisting of hydrogen and deuterium;at least one of R3-R16 is deuterium; andat least one of R3-R16 has deuterium enrichment of no less than about 10%. | ||
| 地址 | La Jolla CA US | ||