Treatment of cancer with TOR kinase inhibitors

摘要

Provided herein are methods for treating or preventing a solid tumor, non-Hodgkin lymphoma or multiple myeloma in a patient, comprising administering an effective amount of a TOR kinase inhibitor to a patient having a solid tumor, non-Hodgkin lymphoma or multiple myeloma.

主权项

1. A method for treating a solid tumor, comprising administering an effective amount of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, to a patient having a solid tumor, wherein the solid tumor is non-small cell lung cancer or breast cancer, and wherein the solid tumor is rapamycin resistant.