Transcatheter valve replacement

摘要

A prosthetic heart valve having an inflow end and an outflow end includes a collapsible and expandable stent, a collapsible and expandable valve assembly disposed within the stent and having a plurality of leaflets, and a deformable frame having a first end and a second end. The frame includes braided wires forming a body having a lumen extending therethrough for receiving the stent and the valve assembly, the body having a plurality of diameters from the first end to the second end.

主权项

1. A prosthetic heart valve having an inflow end and an outflow end, comprising:
a collapsible and expandable stent having a plurality of struts; a collapsible and expandable valve assembly disposed within the stent and having a plurality of leaflets configured to permit a blood flow in a first direction from the inflow end to the outflow end, and to impede the blood flow in a second opposite direction; and a deformable frame having a first end and a second end, the frame including a plurality of shape-memory metallic wires that are braided together to form a three-dimensional body defining an inner surface in contact with struts of the stent, an outer surface for contacting native tissue, the body having a thickness between the inner surface and the outer surface, the thickness being variable from a first distance in an uncompressed state, and a second distance when a force is applied to the body, the second distance being less than the first distance, the body having a lumen extending therethrough for receiving the stent and the valve assembly.