发明名称 |
TARGETED GENE DELIVERY FOR DENDRITIC CELL VACCINATION |
摘要 |
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers. |
申请公布号 |
EP2048955(A4) |
申请公布日期 |
2009.11.25 |
申请号 |
EP20070799765 |
申请日期 |
2007.07.23 |
申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
WANG, PIN;YANG, LILI;BALTIMORE, DAVID |
分类号 |
A01N63/00;A61K38/17 |
主分类号 |
A01N63/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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