发明名称 EDDS CHELATED NANOCERIA WITH CATALASE-LIKE ACTIVITY
摘要 A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, ethylenediaminedisuccinic acid, an oxidant, water, and optionally citric acid, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of cerium oxide nanoparticles. Biocompatible nanoparticles comprised of cerium oxide, ethylenediaminedisuccinic acid, and optionally citric acid, are described. An increase in catalase-like enzyme activity is demonstrated by cerium oxide nanoparticles prepared with citric acid and ethylenediaminedisuccinic acid.
申请公布号 WO2016118592(A1) 申请公布日期 2016.07.28
申请号 WO2016US14076 申请日期 2016.01.20
申请人 CERION, LLC 发明人 BELL, ERIC, LESLIE
分类号 A61K47/12;A61K9/00;A61K9/10;A61K9/14;A61K9/16;A61K33/00;A61K47/18 主分类号 A61K47/12
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