| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a new polypeptide and a biosynthetic pathway. <P>SOLUTION: There are provided the methods and compositions that can be used to produce monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid. Methods are also disclosed for producing indole-3-pyruvate and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid intermediates. Compositions provided include nucleic acid molecules, polypeptides, chemical structures, and cells. Methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions. <P>COPYRIGHT: (C)2010,JPO&INPIT |
