发明名称 |
Tricyclic benzazepine vasopressin antagonists |
摘要 |
Tricyclic compound of the general Formula I: <IMAGE> Formula I as defined herein which exhibit antagonist activity at V1 and/or V2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treating diseases characterized by excess renal reabsorption of water, and process for preparing such compounds.
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申请公布号 |
US5753648(A) |
申请公布日期 |
1998.05.19 |
申请号 |
US19960672150 |
申请日期 |
1996.06.27 |
申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
ALBRIGHT, JAY DONALD;VENKATESAN, ARANAPAKAM M.;DUSZA, JOHN P.;SUM, FUK-WAH |
分类号 |
A61K31/00;A61K31/495;A61K31/4985;A61K31/55;A61K31/551;A61K31/5513;A61K31/5517;A61P1/00;A61P1/16;A61P5/36;A61P5/42;A61P7/00;A61P7/08;A61P7/10;A61P9/00;A61P9/12;A61P13/00;A61P13/12;A61P15/00;A61P15/06;A61P43/00;C07D471/04;C07D471/14;C07D487/04;C07D487/14;(IPC1-7):A61K31/55;C07D487/12;C07D513/00;C07D515/00 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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地址 |
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