| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a method for detecting an endocrine-like substance, more concretely, a method for detecting an endocrine-like substance produced by a long-term metabolism. <P>SOLUTION: The multiple layered cell culture system is obtained by formation of a multiple layer comprising a multiple layered cell culture obtained by formation of a multiple layer comprising a cell layer containing hepatocytes and a cell layer containing one or more kinds of cells selected from the group consisting of vascular endothelial cells, vascular smooth muscle cells, fat cells, hemocyte cells and macrophages and a cell layer containing cells for detecting an endocrine-like substance. The method for detecting an endocrine-like substance comprises using the multiple layered cell culture system. <P>COPYRIGHT: (C)2006,JPO&NCIPI</p> |
