| 发明名称 |
ANDROSTANE AND PREGNANE STEROIDS WITH POTENT ALLOSTERIC GABA RECEPTOR CHLORIDE IONOPHORE MODULATING PROPERTIES |
| 摘要 |
<p>This invention describes compounds of Structures 1, 2, and 3 and their use as allosteric modulators of the GABA receptor chloride ionophore complex to alleviate stress, anxiety, mood disorders, seizures, depression, treatment of drug and alcohol abuse, memory, premenstrual disorders, and neural system damage.</p> |
| 申请公布号 |
EP2155204(A1) |
申请公布日期 |
2010.02.24 |
| 申请号 |
EP20080771137 |
申请日期 |
2008.06.16 |
| 申请人 |
RESEARCH TRIANGLE INSTITUTE;THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
RUNYON, SCOTT, P.;ROGAWSKI, MICHAEL;KEPLER, JOHN;NAVARRO, HERNAN;KAMINSKI, RAFAL;ORR, MATTHEW;COOK EDGAR |
| 分类号 |
A61K31/56;A61P25/02 |
主分类号 |
A61K31/56 |
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