发明名称 |
Formulations of histone deacetylase inhibitor and uses therof |
摘要 |
Dosing regimens, methods of treatment, controlled release formulations, and combination therapies that include an HDAC inhibitor, or a pharmaceutically acceptable salt thereof, are described. |
申请公布号 |
US9403032(B2) |
申请公布日期 |
2016.08.02 |
申请号 |
US201314069233 |
申请日期 |
2013.10.31 |
申请人 |
Pharmacyclics LLC |
发明人 |
Loury David J.;Buggy Joseph J.;Mody Tarak D.;Verner Erik J.;Purro Norbert;Balasubramanian Sriram |
分类号 |
A61K31/166;A61N5/10;A61K45/00;A61K9/20;A61K9/28;A61K9/48;A61K9/50;A61K31/343;A61K31/35;A61K31/381;A61K31/40;A61K31/47;A61K31/497;A61K31/69;A61K47/02;A61K47/12;A61K31/4184;A61K31/573;A61K31/704;A61K45/06;C07D307/85;A61K38/05 |
主分类号 |
A61K31/166 |
代理机构 |
Foley Hoag LLP |
代理人 |
Foley Hoag LLP |
主权项 |
1. A method of treating a hematologic cancer selected from: B-cell lymphoma, Hodgkin lymphoma, chronic lymphocytic leukemia (CLL), and multiple myeloma in an individual in need thereof, comprising administering to the individual a therapeutically-effective amount of Compound 1or a pharmaceutically-acceptable salt thereof. |
地址 |
Sunnyvale CA US |