| 摘要 |
PROBLEM TO BE SOLVED: To provide a treatment regimen utilizing neratinib for breast cancer.SOLUTION: An extended regimen for treatment of HER-2/neu overexpressed/amplified cancer is described, comprising a step of delivering a course of neratinib therapy to HER-2/neu overexpressed/amplified cancer patients following the completion of surgical and adjuvant therapy. The neratinib regimen may be continued for upwards of twelve months to five years. Also provided are pharmaceutical kits designed to facilitate compliance with the regimen. In one aspect, the invention provides a regimen for treatment of HER-2/neu overexpressed/amplified neoplasm, comprising a step of delivering a course of neratinib therapy as an extension of trastuzumab adjuvant therapy, to HER-2/neu overexpressed/amplified cancer patients, e.g., neratinib is delivered following the completion of surgery and standard adjuvant therapy.SELECTED DRAWING: None |
