发明名称 1,3-DIOXANE DERIVATIVES HAVING PROTEIN KINASE C INHIBITORY ACTIVITY
摘要 <p>The present invention provides compounds having formula (I) wherein R1 is alkyl, alkenyl or alkynyl having from 2 to about 20 carbon atoms; R2, R3 and R6 are independently H, phenyl or alkyl having from 1 to about 20 carbon atoms; and R4 and R5 are independently H, R6imino, or amidino, and pharmaceutically acceptable salts thereof which are useful for inhibiting protein kinase C and treating conditions related to, or affected by inhibition of protein kinase C, particularly cancer tumors, inflammatory disease, reperfusion injury, and cardiac dysfunctions related to reperfusion injury.</p>
申请公布号 WO1994010161(A1) 申请公布日期 1994.05.11
申请号 US1992009048 申请日期 1992.10.23
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