发明名称 |
A METHOD FOR THE IDENTIFICATION OF IRS PROTEIN KINASE INHIBITORS OR AGONISTS |
摘要 |
The present invention relates to a method for the identification of an IRS protein kinase inhibitor, comprising the steps of a) bringing into contact P KC- .zeta. with at least one IRS peptide comprising at least one PKC-.zeta.-Ser- phosphorylation site in the presence of at least one putative inhibitor, and b) measuring the phosphorylation of the PKC-.zeta.-Ser-phosphorylation site.
|
申请公布号 |
CA2535649(A1) |
申请公布日期 |
2005.02.24 |
申请号 |
CA20042535649 |
申请日期 |
2004.07.16 |
申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH |
发明人 |
ECKEL, JUERGEN;TENNAGELS, NORBERT;METZGER, SABINE;SOMMERFELD, MARK |
分类号 |
G01N33/573 |
主分类号 |
G01N33/573 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|