| 发明名称 |
INDUCTION OF TOLEROGENIC PHENOTYPE IN MATURE DENDRITIC CELLS |
| 摘要 |
The present invention relates to the use of a CD45 binding molecule to modulate the function of Dendritic cells. In particular the present invention relates to the use of a CD45 binding molecule to induce tolerogenic dendritic cells, useful in the treatment of diseases or disorders such as autoimmune diseases, transplant rejection.
|
| 申请公布号 |
KR20100035643(A) |
申请公布日期 |
2010.04.05 |
| 申请号 |
KR20107000041 |
申请日期 |
2008.06.03 |
| 申请人 |
NOVARTIS AG;FONDAZIONE CENTRO SAN RAFFAELE DEL MONTE TABOR |
发明人 |
CARBALLIDO HERRERA JOSE M.;DE VRIES JAN E.;KORTHAEUER ULF;RONCAROLO MARIA GRAZIA;GREGORI SILVIA ADRIANA |
| 分类号 |
C12N5/0784;A61K35/14;A61P37/00;C07K16/18 |
主分类号 |
C12N5/0784 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
